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While many substances are touted as aphrodisiacs, the modern age of pharmacotherapy began in 1993 when the injection of papaverine, an alpha-receptor blocker that produces vasodilatation, was shown to produce erections when injected directly into the corpora cavernosa. Soon afterwards, other vasodilators, such as PGE1 and phentolamine (Regitine), were demonstrated to be effective either as single agents or in combination.
In the start-and-stop method, you or your partner will stimulate your penis until you feel like you are about to have an orgasm. Then the stimulation stops for about 30 seconds. Once you regain control of your response, stimulation begins again. This process is repeated 3 or 4 times before you allow yourself to have an orgasm.
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(HealthDay News) -- Erectile dysfunction occurs when a man can't achieve or maintain an erection during sex.
FRIDAY, July 21 (HealthDay News) -- The erectile dysfunction drug Uprima did not work for two-thirds of the over 11,000 patients who tried it, according to a U.K. study in the July issue of the urology journal BJU International.
NexMed, Inc. (Nasdaq: NEXM), a specialty CRO and a developer of products based on the NexACT® technology, announced today that it received a Notice of Non-Compliance ("Notice") as part of the review process from Health Canada for its New Drug Submission ("NDS") for the Vitaros erectile dysfunction treatment filed in February 2008. The deficiencies cited related to the product's CMC (Chemistry, Manufacturing and Controls). There were no pre-clinical or clinical deficiencies cited in the Notice. The Notice is a routine end-of-review communication from Health Canada when additional information is needed to reach final decision on product approval.
Risk of infection, bruises, pain, and permanent scarring inside the penis
An inflatable penile prosthesis consists of two soft silicone or bioflex (plastic) tubes inserted in the penis, a small reservoir implanted in the abdomen, and a small pump implanted in the scrotum. To produce an erection, a man pumps sterile liquid from the reservoir into the tubes by squeezing the pump in the scrotum.
An Italian study researched 300 men who had both diabetes and were in the early stages of developing heart disease.
For whatever reason they were taken, NSAIDs roughly doubled the risk of erectile dysfunction compared with non-use. The presence of arthritis without NSAID use increased the risk of erection difficulty by only 30 percent, the researchers explain, and they therefore conclude that NSAIDs were largely to blame for the link between arthritis and erectile dysfunction.
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Dr. Peter Chun-Yip Tong who led the study said: "The development of erectile dysfunction should alert both patients and healthcare providers to the future risk of coronary heart disease."
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Women most likely to suffer from PMS symptoms are between ages 20 and 40, have one child or more, a history of mood disorder or a family member with depression.
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The prescription PDE5 inhibitors sildenafil (Viagra®), vardenafil (Levitra®) and tadalafil (Cialis®) are prescription drugs which are taken orally. They work by blocking the action of PDE5, which causes cGMP to degrade. cGMP causes the smooth muscle of the arteries in the penis to relax, allowing the corpus cavernosum to fill with blood.
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"Prior studies have shown that the oral phosphodiesterase type 5 inhibitor, sildenafil (Viagra, Revatio) improves exercise capacity in patients with pulmonary arterial hypertension," Fonarow said. "This medication is currently FDA-approved for this indication, but must be taken three times daily."
And because impotence -- erectile dysfunction -- manifests itself two to three years sooner than coronary artery disease, the condition essentially serves as a "sentinel of the heart" -- or early warning system for cardiac trouble, a new Italian study found.
Penile biothesiometry: This test involves the use of electromagnetic vibration to determine sensitivity and nerve function. A decreased sensitivity to these vibrations may indicate nerve damage.
"As well as the risk posed by unknown ingredients, internet drugs circumvent traditional healthcare and this poses its own risks as underlying health conditions could go undiagnosed if people don't seek medical advice" says Dr Jackson.
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Neurological (nerve and brain) diseases: The nervous system (the body's system of nerves) plays a vital part in achieving and maintaining an erection and it is common for men with diseases such as stroke, multiple sclerosis (MS), Alzheimer's disease, Parkinson's disease and spinal cord injuries to experience ED. This is due to an interruption in the transmission of nerve impulses between the brain and the penis.
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Yohimbine has a stimulatory effect and side effects include elevated heart rate and blood pressure, mild dizziness, nervousness, and irritability. Yohimbine's effects have not been studied thoroughly, but some studies suggest that 10% to 20% of men respond to treatment with the drug.
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